Larry Cohen, the prolific director of B-movie horror flicks like "It's Alive!" and "The Stuff," has died at the age of 77.

Cohen died Saturday night in Los Angeles surrounded by loved ones, his friend and publicist Shade Rupe told The Hollywood Reporter.

Cohen’s career began in the 1950s on television. He created the TV series "The Invaders" and "Branded," and wrote episodes of "The Fugitive" and "Columbo."

He made his feature film debut with 1972's dark comedy "Bone." From there, he went on to make blaxpoitation films "Black Caesar" and "Hell Up in Harlem."

In 1974, Cohen directed "It's Alive," a horror hit that spawned two sequels. He followed that up with the low-budget horror flicks "God Told Me To" (1976), "Q" (1982), and "The Stuff" (1985).

He most recently wrote the script for 2002's "Phone Booth" starring Colin Farrell and directed an episode of Showtime's "Masters of Horror."

Cohen was the subject of the 2018 documentary, "King Cohen: The Wild World of Filmmaker Larry Cohen," which featured Martin Scorsese, J.J. Abrams, and John Landis.

Cohen also is survived by his second wife, psychotherapist Cynthia Costas Cohen and five children (Pam, Victoria Jill, Melissa, Bobby and Louis), who have all appeared in his movies.