Earth's mightiest heroes defeated all newcomers to rule the box office for a third weekend: "Avengers: Endgame" took in $65 million, bringing its domestic gross to $724 million.

That surpasses the totals of  "Avengers: Infinity War"s ($679 million) and "Black Panther" ($700 million) to become the third-highest grossing movie of all time at the domestic box office. It’s still the second-biggest film ever globally with $2.48 billion, just behind "Avatar"'s $2.78 billion. (James Cameron will have to take out another ad soon: He placed a congratulatory notice when "Endgame" overtook "Titanic.")

In second place this weekend was "Detective Pikachu," starring Ryan Reynolds as the voice of the adorable Pokémon character and Justice Smith as his new partner.  It pulled in a solid $58 million from 4,202 venues.

That's the best-ever debut for a movie based on a video game ever, topping "Lara Croft: Tomb Raider," which opened in 2001 with $47.7 million.

Audiences give the film an "A-" CinemaScore.

Despite lousy reviews, the Rebel Wilson and Anne Hathaway con-woman comedy "The Hustle" launched on the higher end of expectations with $13.5 million from 3,007 screens. The remake of "Dirty Rotten Scoundrels" and "Bedtime Story" has a 16% critics rating on Rotten Tomatoes.

Bad reviews didn't help Diane Keaton cheerleading comedy “Poms,” which debuted with a  disappointing $5.1 million. The movie played to an older female audience, with women representing 75% of opening weekend crowds. Critics gave it 29% on Rotten Tomatoes, but audiences were kinder, with a "B+" CinemaScore.

"Tolkien,” a biographical drama starring  Nicholas Hoult  as "Lord of the Rings" author J. R. R. Tolkien, debuted in ninth place with $2 million from 1,495 locations. It's the first Fox Searchlight title to be distributed by Disney since the studio purchased Fox’s film assets.

It didn't fare well with critics, who gave it a 49% Rotten Tomatoes critics rating, but audiences have so far given it a far more positive 85%.

The highest per-screen-average of the weekend went to the documentary "The Biggest Little Farm," which debuted with $101,000 from five locations, averaging out to $20,000 per venue. It's about a couple who filmed their 8-year journey to create a sustainable farm near Los Angeles.

Here are the top 10 estimates for May 10-12, 2019

1. "Avengers: Endgame," $63,054,000
2 . "Pokémon Detective Pikachu," $58,000,000
3. "The Hustle," $13,536,298
4. "The Intruder" (2019), $6,600,000
5. "Long Shot," $6,125,000
6.  "Poms," $5,110,000
7. "UglyDolls," $3,920,000
8. "Breakthrough," $2,466,000
9. "Tolkien," $2,153,000
10. "Captain Marvel,"$1,813,000

[Via Variety, Box Office Mojo]