Tot Watchers (1958)

The lady of the house has gone out for a few hours, leaving her baby in the care of a stereotypical 1950s teenager, who immediately begins calling her friends. Tom and Jerry must call a truce to their constant chases as the baby, unsupervised, continually gets loose. When the baby escapes out the front door, Tom and Jerry chase it to a construction site, where they frantically try to keep it from harm.